Table 2 Association between baseline frailty and risk of cancer
Group | Number of cases | Person-years | Model 1Â h (95% CI) | Model 2Â h (95% CI) | Model 3Â h (95% CI) |
|---|---|---|---|---|---|
Non-frailty | 107 | 477 | 1.00 | 1.00 | 1.00 |
Pre-frailty | 116 | 482 | 1.31 (1.01,1.71) | 1.34 (1.03,1.75) | 1.34 (1.03,1.75) |
Frailty | 25 | 100 | 1.59 (1.03,2.46) | 1.66 (1.07,2.56) | 1.66 (1.07,2.56) |
Increase in frailty index per 0.1 | Â | Â | 1.21 (1.06,1.37) | 1.22 (1.07,1.39) | 1.22 (1.07,1.39) |
Grouped by age | Â | Â | Â | Â | Â |
< 60 years old |  |  |  |  |  |
Non-frailty | 62 | 174 | 1.00 | 1.00 | 1.00 |
Pre-frailty | 57 | 262 | 1.48 (1.03,2.12) | 1.46 (1.01,2.10) | 1.42 (0.98,2.06) |
Frailty | 9 | 68 | 2.01 (1.00,4.04) | 1.98 (0.98,4.01) | 1.92 (0.94,3.93) |
Increase in frailty index per 0.1 | Â | Â | 1.28 (1.05,1.56) | 1.27 (1.03,1.55) | 1.25 (1.01,1.55) |
≥ 60 years old |  |  |  |  |  |
Non-frailty | 45 | 304 | 1.00 | 1.00 | 1.00 |
Pre-frailty | 59 | 220 | 1.05 (0.71,1.55) | 1.11 (0.75,1.65) | 1.09 (0.73,1.612) |
Frailty | 16 | 32 | 1.18 (0.67,2.09) | 1.32 (0.74,2.35) | 1.25 (0.69,2.257) |
Increase in frailty index per 0.1 | Â | Â | 1.11 (0.93,1.33) | 1.12 (0.97,1.39) | 1.14 (0.95,1.374) |
Grouped by sex | Â | Â | Â | Â | Â |
Male | Â | Â | Â | Â | Â |
Non-frailty | 61 | 241 | 1.00 | 1.00 | 1.00 |
Pre-frailty | 44 | 193 | 1.13 (0.76,1.66) | 1.06 (0.71,1.57) | 1.04 (0.70,1.55) |
Frailty | 9 | 35 | 1.52 (0.76,3.07) | 1.36 (0.67,2.77) | 1.33 (0.64,2.74) |
Increase in frailty index per 0.1 | Â | Â | 1.15 (0.93,1.42) | 1.10 (0.88,1.37) | 1.09 (0.87,1.37) |
Female | Â | Â | Â | Â | Â |
Non-frailty | 46 | 237 | 1.00 | 1.00 | 1.00 |
Pre-frailty | 72 | 289 | 1.51 (1.04,2.19) | 1.56 (1.07,2.27) | 1.51 (1.03,2.21) |
Frailty | 16 | 65 | 1.71 (0.97,3.025) | 1.83 (1.02,3.28) | 1.70 (0.93,3.10) |
Increase in frailty index per 0.1 | Â | Â | 1.25 (1.06,1.47) | 1.28 (1.08,1.52) | 1.26 (1.05,1.50) |