Table 5 Sensitivity analysis for CVD and all-cause mortality associated with excluded participants with history of diabetes, hypertension, or kidney conditions

CVD mortality

Deaths, No. (%)

6(0.27)

9(0.88)

11(0.98)

5(0.30)

6(0.22)

16(0.78)

Deaths/person-years

149,324/128,998,453

830,208/93,217,485

525,651/104,109,044

296,014/126,830,071

184,852/114,489,317

1,491,136/198,236,158

Unadjusted

1 [Reference]

3.40(0.94,12.27)

4.14(1.03,16.60)*

1.23(0.30,4.97)

0.89(0.23,3.51)

3.21(1.07,9.65)*

Model 1

1 [Reference]

2.28(0.63,8.20)

3.31(0.78,14.05)

1.06(0.23,4.84)

0.71(0.16,3.13)

2.66(0.77,9.17)

Model 2

1 [Reference]

2.10(0.59,7.43)

2.77(0.73,10.59)

0.98(0.21,4.65)

0.63(0.13,2.96)

2.41(0.68,8.57)

Model 3

1 [Reference]

2.15(0.62,7.40)

2.74(0.73,10.19)

0.93(0.20,4.43)

0.62(0.14,2.81)

2.35(0.66,8.34)

All-Cause Mortality

Deaths, No. (%)

28(1.58)

36(3.63)

40(3.92)

42(2.49)

27(2.26)

39(2.02)

Deaths/person-years

1,362,269/128,998,453

2,520,822/93,217,485

2,386,005/104,109,044

2,217,032/126,830,071

1,624,188/114,489,317

3,028,538/198,236,158

Unadjusted

1 [Reference]

2.37(1.26,7.73)*

2.65(1.50,4.68)*

1.69(0.94,3.02)

1.51(0.77,2.96)

1.37(0.77,2.43)

Model 1

1 [Reference]

1.69(0.91,3.12)

1.97(1.07,3.64)*

1.45(0.78,2.71)

1.14(0.53,2.44)

1.13(0.59,2.17)

Model 2

1 [Reference]

1.60(0.86,2.97)

1.80(0.97,3.34)

1.38(0.75,2.57)

1.12(0.52,2.44)

1.10(0.57,2.09)

Model 3

1 [Reference]

1.62(0.87,3.03)

1.80(0.97,3.35)

1.34(0.73,2.46)

1.13(0.53,2.41)

1.09(0.57,2.08)