Table 4 Sensitivity analysis for CVD and all-cause mortality associated with excluded participants with mortality in the first year

CVD mortality

Deaths, No. (%)

13(0.37)

19(1.06)

25(1.38)

22(0.90)

17(0.77)

32(1.08)

Deaths/person-years

367,166/184,600,398

1,219,535/129,259,880

1,330,670/136,402,700

1,141,765/171,410,817

840,874/158,859,519

2,627,762/262,320,437

Unadjusted

1 [Reference]

3.19(1.51,6.74)*

4.75(2.45,9.23)**

2.80(1.33,5.86)*

2.41(1.04,5.59)*

3.29(1.89,5.74)**

Model 1

1 [Reference]

2.04(0.99,4.23)

3.47(1.76,6.82)**

2.47(1.17,5.22)*

2.15(0.92,5.06)

2.83(1.46,5.50)*

Model 2

1 [Reference]

2.00(0.97,4.12)

3.71(1.90,7.26)**

2.52(1.15,5.52)*

2.27(0.94,5.51)

3.06(1.55,6.01)*

Model 3

1 [Reference]

2.00(0.94,4.25)

3.95(1.95,8.01)**

2.56(1.13,5.79)*

2.42(1.01,5.79)*

2.94(1.52,5.67)*

All-Cause Mortality

Deaths, No. (%)

61(2.42)

75(4.52)

84(5.62)

98(4.13)

60(3.44)

96(3.03)

Deaths/person-years

2,957,257/184,600,398

4,379,695/129,259,880

4,853,238/136,402,700

5,215,243/171,410,817

3,652,921/158,859,519

6,167,197/262,320,437

Unadjusted

1 [Reference]

2.08(1.43,3.02)**

2.72(1.87,3.96)**

1.91(1.33,2.75)**

1.53(0.96,2.46)

1.42(0.94,2.14)

Model 1

1 [Reference]

1.52(1.04,2.23)*

2.17(1.45,3.24)**

1.76(1.18,2.62)*

1.33(0.81,2.18)

1.25(0.79,1.99)

Model 2

1 [Reference]

1.39(0.94,2.06)

2.03(1.35,3.07)*

1.66(1.11,2.50)*

1.35(0.82,2.23)

1.27(0.80,2.00)

Model 3

1 [Reference]

1.38(0.94,2.02)

2.13(1.41,3.23)**

1.67(1.12,2.49)*

1.40(0.85,2.28)

1.28(0.83,1.98)