Table 3 Hazard ratios and 95% confidence intervals for dementia onset over 5 years

IADL ability based on the NCGG-ADL

NCGG-ADL score, points

0.72 (0.61–0.84)

0.87 (0.71–1.05)

0.88 (0.73–1.07)

IADL limitation based on the NCGG-ADL

Participants without IADL limitation

Reference

Reference

Reference

Participants with IADL limitation

2.47 (1.69–3.60)

1.59 (1.07–2.37)

1.55 (1.04–2.31)

Combination of MCI and IADL limitation

Unimpaired cognition without IADL limitation

Reference

Reference

Reference

Unimpaired cognition with IADL limitation

2.49 (1.48–4.18)

1.56 (0.92–2.67)

1.53 (0.90–2.61)

MCI without IADL limitation

2.47 (1.70–3.57)

1.96 (1.35–2.85)

1.87 (1.28–2.74)

MCI with IADL limitation

4.92 (2.89–8.37)

3.03 (1.74–5.27)

2.88 (1.65–5.03)

P-value for trend

< 0.001

< 0.001

< 0.001