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Table 1 Characteristics of sample population (N = 185)

From: Measuring (Mis)trust in the age of COVID-19: viewpoints of vaccine clinical trial participation among individuals living with sickle cell disease

 

Total sample

N (%)

Views on importance of people taking part in COVID-19 vaccine research

Views on the utility of COVID-19 vaccine research

  

Agree

N (%)

No Opinion/Disagree

N (%)

p-value

Agree

N (%)

No Opinion/Disagree

N (%)

p-value

TOTAL

185

132 (71.4)

53 (28.6)

-

111 (60.0)

74 (40.0)

-         

Age

   

0.33

  

0.62

 Mean [Range]

36.6 [18–68]

37.1 [18–68]

35.4 [19–67]

36.9 [18–68]

36.1 [19–67]

  (SD)

-10.7

-10.7

-10.7

-10.5

-11.1

Gender

   

0.17

  

0.01

 Female

115 (62.2)

78 (42.1)

37 (20.0)

61 (33.0)

54 (29.2)

 Male

70 (37.8)

54 (29.2)

16 (8.7)

50 (27.0)

20 (10.8)

Genotype

   

0.88

  

0.29

 HbSS

118 (63.8)

84 (45.4)

34 (18.4)

67 (36.2)

51 (27.6)

 HbSC

32 (17.3)

22 (11.9)

10 (5.4)

19 (10.3)

13 (7.0)

 Other Genotype a

35 (18.9)

26 (14.0)

9 (4.9)

25 (13.5)

10 (5.4)

Race*

   

< 0.001

  

< 0.001

 American Indian/Alaska Native

1 (0.6)

-

1 (0.6)

-

1 (0.6)

 Black/African American

154 (85.6)

108 (60.0)

46 (25.6)

91 (50.6)

63 (35.0)

 Native Hawaiian/Pacific Islander

2 (1.1)

2 (1.1)

-         

1 (0.6)

1 (0.6)

 White

16 (8.9)

15 (8.3)

1 (0.6)

16 (8.9)

-

 Other b

7 (3.9)

7 (3.9)

-

2 (1.1)

5 (2.8)

Ethnicity*

   

0.81

  

0.96

 Not Hispanic/Latino

160 (88.9)

116 (64.4)

44 (24.4)

95 (52.8)

65 (36.1)

 Hispanic/Latino

20 (11.1)

14 (7.8)

6 (3.3)

12 (6.7)

8 (4.4)

Income*

   

0.01

  

0.01

 $59,999 or less

78 (43.8)

64 (36.0)

14 (7.8)

53 (29.8)

22 (12.4)

 $60,000 or greater

100 (56.2)

64 (36.0)

36 (20.2)

56 (31.5)

47 (26.4)

Education

       

 High school Degree/Some College

81 (43.8)

56 (30.3)

25 (13.5)

0.56

43 (23.2)

38 (20.5)

 

 Bachelor’s or Higher

104 (56.2)

76 (41.1)

28 (15.1)

 

68 (36.8)

36 (19.5)

0.09

Insurance Status

   

0.44

  

0.58

 Insured

170 (91.9)

120 (64.9)

50 (27.0)

101 (54.6)

69 (37.3)

 Not Insured

15 (8.1)

12 (6.5)

3 (1.6)

10 (5.4)

5 (2.7)

Employment Status*

   

0.07

  

0.01

 Employed

98 (55.7)

75 (42.6)

23 (13.1)

67 (38.1)

31 (17.6)

 Not employed

78 (44.3)

50 (28.4)

28 (15.9)

37 (21.0)

41 (23.3)

Marital Status

   

0.32

  

0.19

 Married

91 (49.2)

68 (36.8)

23 (12.4)

59 (31.9)

32 (17.3)

 Unmarried

94 (50.8)

64 (34.6)

30 (16.2)

52 (28.1)

42 (22.7)

Healthcare Providerc

   

0.1

  

0.46

 Yes

173 (93.5)

126 (68.1)

47 (25.4)

105 (56.8)

68 (36.8)

 No

12 (6.5)

6 (3.2)

6 (3.2)

6 (3.2)

6 (3.2)

Worried about COVID-19 Infection

       

 Any level of worry d

155 (83.8)

117 (63.2)

38 (20.5)

0.005

99 (53.5)

56 (20.3)

0.01

 Not worried

30 (16.2)

15 (8.1)

15 (8.1)

 

12 (6.5)

18 (9.7)

 

Sickle Cell Disease Severity Score

       

 Mean [Range],

2.9 [0–8]

3.1 [0–8]

2.4 [0–6]

0.02

3.3 [0–8]

2.4 [0–7]

< 0.001

  (SD)

-2

-2

-1.8

 

-2

-1.8

 

Medical Mistrust

 

2.9 [1.2-4] (0.5)

 

0.25

  

0.03

 Mean [Range]

2.9 [1–4]

3.0 [1.9–3.9]

2.8 [1.2-4]

3.0 [1.9-4]

 (SD)

-0.6

-0.6

-0.6

-0.5

  1. aOther genotype includes Hb Sß+-Thalassemia, Hb Sß0-Thalassemia, Sickle HPFH, Sickle Delta Beta (0) Thalassemia, Sickle HbO-Arab, Sickle HbE
  2. bOther includes: White/Hispanic or Other/Mixed
  3. cDo you have a doctor or nurse you usually see if you need a check up, want advice about a health problem, or get sick or hurt?
  4. dAny level of worry includes slightly, moderately, very, or extremely worried of infection
  5. * Totals reflect complete data after the removal of missing responses.
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