Skip to main content

Table 2 Associations between social isolation and risk of seven progressions of frailty using the Markov state-transition model

From: Social isolation in relation to the incidence and dynamic progression of frailty in the oldest old: a trajectory analysis of a nationwide cohort

Progressions of frailty

Model 1

Model 2

Model 3

Model 4

HR

95% CI

HR

95% CI

HR

95% CI

HR

95% CI

Non-frailty to prefrailty

1.108

(1.072 ∼ 1.145)

1.075

(1.041 ∼ 1.111)

1.047

(1.012 ∼ 1.083)

1.042

(1.007 ∼ 1.079)

Non-frailty to death

1.265

(1.003 ∼ 1.595)

1.123

(0.979 ∼ 1.289)

1.142

(0.992 ∼ 1.316)

1.125

(0.979 ∼ 1.294)

Prefrailty to non-frailty

0.780

(0.739 ∼ 0.823)

0.965

(0.918 ∼ 1.014)

0.961

(0.913 ∼ 1.011)

0.960

(0.912 ∼ 1.010)

Prefrailty to frailty

1.205

(1.171 ∼ 1.240)

1.042

(1.011 ∼ 1.075)

1.043

(1.010 ∼ 1.076)

1.039

(1.007 ∼ 1.073)

Prefrailty to death

1.265

(1.231 ∼ 1.301)

1.173

(1.114 ∼ 1.235)

1.146

(1.086 ∼ 1.210)

1.161

(1.099 ∼ 1.226)

Frailty to prefrailty

0.877

(0.806 ∼ 0.954)

1.013

(0.952 ∼ 1.078)

0.986

(0.926 ∼ 1.050)

0.991

(0.930 ∼ 1.056)

Frailty to death

1.110

(1.083 ∼ 1.138)

1.043

(1.019 ∼ 1.068)

1.030

(1.006 ∼ 1.056)

1.029

(1.004 ∼ 1.054)

  1. Note: Model 1: Basic model was non-adjusted. Model 2: Adjusted for age and sex at baseline. Model 3: Adjusted for age, sex, education, household income and residence at baseline. Model 4: Adjusted for age, sex, education, household income, residence, childhood socioeconomic status, intake of vegetables and fruits, smoking, drinking and regular physical exercise at baseline. Significant results are marked in bold
  2. Abbreviations: HR, hazard ratios; 95% CI, 95% confidence interval