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Table 3 Sensitivity analysese of sedentary behavior and physical activity associations with current chronic disease burden (CCIcurrent)

From: Current and historic patterns of chronic disease burden are associated with physical activity and sedentary behavior in older adults: an observational study

  

CCIcurrent = 0

N = 515

CCIcurrent = 1

N = 137

β1vs.0 (95% CI)

CCIcurrent = 2

N = 114

β2vs.0 (95% CI)

CCIcurrent = 3+

N = 120

β3+vs.0 (95% CI)

P-valued

Sedentary Behavior Measures

Daily Total Sitting (minutes)a

Reference

6.1 (-16.2, 28.4)

18.6 (-7.8, 45.0)

36.5 (10.7, 62.2)

0.042*

Mean Bout Duration (minutes)a

Reference

-0.7 (-1.8, 0.4)

2.3 (0.3, 4.3)

2.3 (0.2, 4.4)

0.003*

Sitting bouts > 30 min (n/day)a

Reference

0.0 (-0.3, 0.4)

0.1 (-0.3, 0.4)

0.3 (0.0, 0.6)

0.342

Sit-to-stand transitions (n/day)a

Reference

0.9 (-1.4, 3.2)

-1.6 (-4.4, 1.2)

-2.3 (-5.1, 0.5)

0.167

Light-Intensity Movement Measures

Standing Time (minutes)a

Reference

-1.3 (-21.1, 18.5)

-9.9 (-34.0, 14.1)

-19.1 (-41.9, 3.6)

0.389

LPA (minutes)b, c

Reference

-7.8 (-19.9, 4.3)

-16.6 (-30.9, -2.3)

-12.2 (-27.2, 2.7)

0.087

Moderate-to-Vigorous Intensity Movement Measures

Stepsa

Reference

-417 (-907, 74)

-848 (-1450, -246)

-1516 (-2085, -946)

< 0.001*

MVPA (minutes)b, c

Reference

-2.9 (-9.4, 3.5)

-9.0 (-16.1, -1.9)

-19.2 (-25.8, -12.6)

< 0.001*

  1. a activPAL measures: daily total sitting time, mean sitting bout duration, number daily sitting bouts > 30 min, number daily sit-to-stand transitions, daily total standing time, daily total steps
  2. b ActiGraph measures: daily total LPA, daily total MVPA
  3. c LPA and MVPA defined using Objective Physical Activity and Cardiovascular Health in older Women (OPACH) cutpoints, which are validated for an older adult population
  4. d P-value corresponds to a joint (omnibus) test of the 3 parameters corresponding to the exposure contrasts (β1vs.0, β2vs.0, β3+vs.0)
  5. e Sensitivity analyses in which CCIcurrent is modeled as a categorical variable (0, 1, 2, 3+) rather than as a continuous term; model adjusted for age, sex, race/ethnicity, education, BMI, depressive symptoms, and device wear time
  6. Notes: CCI = Charlson Comorbidity Index; CI = Confidence Interval; PA = Physical Activity; LPA = Light-Intensity Physical Activity; MVPA = Moderate-to-Vigorous Physical Activity
  7. *Statistically significant associations at the p < 0.05 level