Table 4 Scenario analysis results
| Â | Â | Incremental vs. No vaccination | ||
|---|---|---|---|---|
| Â | Â | Q-Q with herd effect (entire US population) | N-Q high VCR | Q-P-B |
Number of IMD cases | Total | -631 | -156 | -280 |
Serogroup A | 0 | 0 | 0 | |
Serogroup B | 0 | 0 | -5 | |
Serogroup C | -369 | -99 | -166 | |
Serogroup W | -4 | -2 | -2 | |
Serogroup Y | -257 | -56 | -107 | |
Number of IMD deaths | -143 | -38 | -61 | |
Number of long-term survivors with sequelae | -90 | -22 | -40 | |
Total QALYs lost | -3,711 | -1,229 | -2,059 | |
Cost of vaccination (2023 USD) | 1,082.7Â M | 550.8Â M | 1,561.1Â M | |
Cost of IMD (2023 USD) | -69.3Â M | -17.2Â M | -30.7Â M | |
Cost of sequalae (2023 USD) | -39.4Â M | -9.5Â M | -17.7Â M | |
Total direct medical costs (2023 USD) | -108.7Â M | -26.7Â M | -48.5Â M | |
Total direct costs (2023 USD) | 974.0Â M | 524.0Â M | 1,512.6Â M | |
Indirect costs (2023 USD) | -267.8Â M | -91.1Â M | -143.6Â M | |
TOTAL costs (2023 USD) | 705.2Â M | 433.0Â M | 1,369.1Â M | |
ICER per QALY gained (2023 USD) | 190,030 | 352,169 | 664,767 | |