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Table 1 Population characteristics included in the study

From: Associations of ambient air pollution and lifestyle with the risk of NAFLD: a population-based cohort study

Characteristics

Total

(n = 417,025)

Individuals without NAFLD

(n = 412,273)

Individuals with NAFLD

(n = 4,752)

P value

Sex [n (%)]

   

0.002

 Female

223,892 (53.7)

221,446 (53.7)

2446 (51.5)

 

 Male

193,133 (46.3)

190,827 (46.3)

2306 (48.5)

 

Age [mean ± SD]

56.30 ± 8.12

56.29 ± 8.12

56.82 ± 7.93

< 0.001

Age [n (%)]

   

0.017

 < 60

241,067 (57.8)

238,401 (57.8)

2666 (56.1)

 

 ≥ 60

175,958 (42.2)

173,872 (42.2)

2086 (43.9)

 

Ethnicity [n (%)]

   

0.005

 White

392,478 (94.1)

388,051 (94.1)

4427 (93.2)

 

 Others

24,547 (5.9)

24,222 (5.9)

325 (6.8)

 

BMI [mean ± SD]

27.44 ± 4.79

27.39 ± 4.76

31.45 ± 5.69

< 0.001

BMI [n (%)]

   

< 0.001

 Normal (< 25 kg/m2)

136,727 (32.8)

136,261 (33.1)

466 (9.8)

 

 Overweight (25–29.9 kg/m2)

176,670 (42.4)

175,008 (42.4)

1662 (35.0)

 

 Obesity (≥ 30 kg/m2)

101,353 (24.3)

98,781 (24.0)

2572 (54.1)

 

 Missing

2275 (0.5)

2223 (0.5)

52 (1.1)

 

24-h weighted average noise [n (%)]

   

0.130

 ≤ 55 dB[A]

215,380 (51.6)

212,934 (51.6)

2446 (51.5)

 

 > 55 to ≤ 60 dB[A]

150,445 (36.1)

148,716 (36.1)

1729 (36.4)

 

 > 60 to ≤ 65 dB[A]

24,576 (5.9)

24,327 (5.9)

249 (5.2)

 

 > 65 dB[A]

26,624 (6.4)

26,296 (6.4)

328 (6.9)

 

Household income [n (%)]

   

< 0.001

 Less than £31,000

168,999 (40.5)

166,633 (40.4)

2366 (49.8)

 

 Equal to or above £31,000

184,468 (44.2)

182,963 (44.4)

1505 (31.7)

 

 Missing

63,558 (15.2)

62,677 (15.2)

881 (18.5)

 

TDI [n (%)]

   

< 0.001

 Tertile1

138,845 (33.3)

137,691 (33.4)

1154 (24.3)

 

 Tertile2

138,852 (33.3)

137,472 (33.3)

1380 (29.0)

 

 Tertile3

138,857 (33.3)

136,644 (33.1)

2213 (46.6)

 

 Missing

471 (0.1)

466 (0.1)

5 (0.1)

 

Education level [n (%)]

   

< 0.001

 Degree or professional education

131,228 (31.5)

130,240 (31.6)

988 (20.8)

 

 Other levels

277,924 (66.6)

274,288 (66.5)

3636 (76.5)

 

 Missing

7873 (1.9)

7745 (1.9)

128 (2.7)

 

Employment status [n (%)]

   

< 0.001

 Paid

243,407 (58.4)

241,062 (58.5)

2345 (49.3)

 

 Not employed or not in paid

171,958 (41.2)

169,572 (41.1)

2386 (50.2)

 

 Missing

1660 (0.4)

1639 (0.4)

21 (0.4)

 

Greenspace percentage in 1000 m buffer [n (%)]

   

< 0.001

 Low

197,043 (47.2)

194,516 (47.2)

2527 (53.2)

 

 High

197,052 (47.3)

194,938 (47.3)

2114 (44.5)

 

 Missing

22,930 (5.5)

22,819 (5.5)

111 (2.3)

 

Proximity to major road [n (%)]

   

0.034

 Low

208,440 (50.0)

206,138 (50.0)

2302 (48.4)

 

 High

208,585 (50.0)

206,135 (50.0)

2450 (51.6)

 

Lifestyle factor

    

Lifestyle score [n (%)]

   

< 0.001

 0

45,380 (10.9)

45,136 (10.9)

244 (5.1)

 

 1

98,862 (23.7)

98,039 (23.8)

823 (17.3)

 

 2

100,798 (24.2)

99,683 (24.2)

1115 (23.5)

 

 3

54,888 (13.2)

54,122 (13.1)

766 (16.1)

 

 4

18,193 (4.4)

17,872 (4.3)

321 (6.8)

 

 ≥ 5

3768 (0.9)

3685 (0.9)

83 (1.7)

 

 Missing

95,136 (22.8)

93,736 (22.7)

1400 (29.5)

 

Lifestyle [n (%)]

   

< 0.001

 Mostly healthy

45,380 (10.9)

45,136 (10.9)

244 (5.1)

 

 Moderately healthy

199,660 (47.9)

197,722 (48.0)

1938 (40.8)

 

 Least healthy

76,849 (18.4)

75,679 (18.4)

1170 (24.6)

 

 Missing

95,136 (22.8)

93,736 (22.7)

1400 (29.5)

 

Air pollution, µg/m3

    

NO2 [median (Q1, Q3)]

26.13 (21.38, 31.21)

26.12 (21.37, 31.19)

27.80 (22.91, 32.51)

< 0.001

NOx [median (Q1, Q3)]

42.23 (34.22, 50.72)

42.20 (34.19, 50.69)

44.72 (36.69, 53.55)

< 0.001

PM2.5 [median (Q1, Q3)]

9.93 (9.29, 10.56)

9.93 (9.29, 10.56)

10.11 (9.49, 10.79)

< 0.001

PM10 [median (Q1, Q3)]

16.03 (15.25, 17.01)

16.03 (15.25, 17.01)

16.11 (15.42, 17.15)

< 0.001

PM2.5−10 [median (Q1, Q3)]

6.11 (5.84, 6.64)

6.11 (5.84, 6.64)

6.14 (5.86, 6.72)

< 0.001

  1. Abbreviations: NO2, nitrogen dioxide; NOx, nitrogen oxides; PM2.5, particulate matter with aerodynamic diameter ≤ 2.5 μm; PM10, particulate matter with aerodynamic diameter ≤ 10 μm; PM2.5−10, particulate matter with aerodynamic diameter in 2.5–10 μm; BMI, body mass index; SD, standard deviation; Q, quartile